THE EFFECT OF INCOME, HISTORY OF SMOKING, SIDE EFFECTS AND MEDICATION ADHERENCE TO DRUG RESISTANT TUBERCULOSIS IN HAJI ADAM MALIK GENERAL HOSPITAL MEDAN 2018

Abstract

Background: Drug-resistant TB (TB RO) is a condition in which Mycobacterium tuberculosis can no longer be killed with one or more anti-tuberculosis drugs (OAT). Purpose. This study aims to analyze income, smoking history, side effects and medication adherence to the incidence of drug-resistant TB at RSUP H. Adam Malik Medan 2018.

Materials and Methods: This type of research is an analytical observational study with a case control study design with a case sample size of 34 people and a control sample of 68 people. Primary data were collected using a questionnaire and secondary data were obtained from medical records and analyzed using Multiple Logistic Regression.

Result: The result of the study, was found that income, smoking history, side effects and medication adherence had an effect on the incidence of drug-resistant TB where drug side effects were the dominant factor with OR = 21,468, meaning that patients who experienced drug side effects had a risk of 21,468 times experienced drug-resistant TB compared with patients who did not experience the side effects of the drug.

Conclusion: Based on the research, drug side effects were the dominant factor to experience drug resistant tuberculosis. It is hoped that the Poli TB DOTS and MDR TB officers at RSUP Haji Adam Malik Medan can provide information intensively to patients about the side effects of drugs that patients will suffer during treatment and continue to motivate patients so that patients can endure the side effects they suffer for healing sufferer.

Keywords: Side effect, drug resistant tuberculosis