RISK ESTIMATION OF PULMONARY TUBERCULOSIS ON HIV/AIDS PATIENTS: A META-ANALYSIS OF CROSS-SECTIONAL STUDY
Background: Pulmonary tuberculosis is still one of the diseases that burdened the world. One of its factor risk was HIV/AIDS. However, risk values of tuberculosis by HIV/AIDS had various numbers. This study was aimed to estimate the risk of pulmonary tuberculosis and HIV/AIDS with meta-analysis.
Materials and Methods: We searched seven journal databases to find cross-sectional studies with odd ratios (ORs) and their 95% confidence intervals (CIs). Statistical analyses were carried out by Comprehensive Meta-Analysis version 2. Heterogeneity were analyzed by using p value derived from Q statistics. Random effects model was used for this analysis.
Result: We identified 22 journals from title and abstract screening, but only 4 journals were eligible for analysis. We found that people with HIV/AIDS had higher risk of pulmonary tuberculosis of 2.696 times than people without HIV/AIDS. There was no heterogeneity or publication bias found on this analysis. However, this study had low number of eligible journal analyzed. It also had low proportion of population with HIV and without HIV.
Conclusion: People HIV/AIDS are at risk of pulmonary tuberculosis 2.696 times larger than people without HIV/AIDS. Further research was needed to find more accurate results of HIV/AIDS risk values of tuberculosis.Keywords: pulmonary tuberculosis, HIV/AIDS, meta-analysis, risk estimation