EFFECT OF WATER CLOVER (MARSILEA CRENATA) EXTRACT ON TRIGLICERYDES OF THE HYPERTRIGLYCERIDES RATS
Background: High levels of triglyceride (TG) is a risk factor in cardiovascular disease. The flavonoids in water clover contain 10,58 mg of extract. This research aims to prove that flavonoids can decrease triglyceride.
Materials and Methods: True experimental study used design pre-post test control group design. The sample was selected based on by completed randomized design sampling to be devided into five groups, the negative control (n=5) were only given normal diet, positive control (n=5) were only given high cholesterol diet and treatment groups with three doses water clover extract (n=15) were given cholesterol diet during the 14 days and water clover extract for 14 days. Statistical analysis used Paired Sample T-Test and MANOVA (Multivariate Analyses of Variance).
Result: The results of this research can decreased TG levels as an effect of water clover extract before and after treatment, that there was significant (p. < 0.05). Levels of triglycerides in negative control group compared with positive control and third treatment showed a significant difference (p.< 0.05).
Conclusion: Conclusions of this research is water clover extract has effect to decrease TG levels significantly.
Keywords: hypertriglyceridemia, Water Clover, flavonoid